产品
编 号：F336262
分子式：C24H28N2O4
分子量：408.49
分子式：C24H28N2O4
分子量：408.49
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 3614-69-5
产品详情
生物活性：
Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions.
体内研究：
Dimethindene maleate (0.25 mg; i.p. once) affects wound healing in mice.Animal Model:C57BL/6 mice with wound healing
Dosage:0.25 mg
Administration:Intraperitoneal injection; 0.25 mg once
Result:Significantly delayed skin wound and only showed wound closure impairment in the initial phase wound healing.
体外研究：
Dimethindene maleate (1-1000 μM) suppresses the cromakalim-induced/glibenclamide-sensitive K＋ currents in a concentration-dependent and reversible manner with an IC50 value of 29.5 μM.Dimethindene maleate (1-1000 μM) inhibits Y-26763-induced glibenclamide-sensitive K＋ currents with an IC50 value of 49 μM.
Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions.
体内研究：
Dimethindene maleate (0.25 mg; i.p. once) affects wound healing in mice.Animal Model:C57BL/6 mice with wound healing
Dosage:0.25 mg
Administration:Intraperitoneal injection; 0.25 mg once
Result:Significantly delayed skin wound and only showed wound closure impairment in the initial phase wound healing.
体外研究：
Dimethindene maleate (1-1000 μM) suppresses the cromakalim-induced/glibenclamide-sensitive K＋ currents in a concentration-dependent and reversible manner with an IC50 value of 29.5 μM.Dimethindene maleate (1-1000 μM) inhibits Y-26763-induced glibenclamide-sensitive K＋ currents with an IC50 value of 49 μM.
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