产品
编 号：F336458
分子式：C18H24O3
分子量：288.38
分子式：C18H24O3
分子量：288.38
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 362-05-0
产品详情
生物活性：
2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity.
体内研究：
2-Hydroxyestradiol attenuated the development of obesity and improved endothelial function, decreased nephropathy, decreased the severity of diabetes, lowered arterial blood pressure, and reduced plasma cholesterol.
体外研究：
2-Hydroxyestradiol induces phenotypical changes indicative of neoplastic transformation.2-Hydroxyestradiol (2-OHE2) is capable of in vitro transforming a HBEC, MCF-10F cell line, that is estrogen receptor-a (ERα) negative and ERβ positive.2-Hydroxyestradiol induces oxidative DNA damage and apoptosis in human mammary epithelial cells.
2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity.
体内研究：
2-Hydroxyestradiol attenuated the development of obesity and improved endothelial function, decreased nephropathy, decreased the severity of diabetes, lowered arterial blood pressure, and reduced plasma cholesterol.
体外研究：
2-Hydroxyestradiol induces phenotypical changes indicative of neoplastic transformation.2-Hydroxyestradiol (2-OHE2) is capable of in vitro transforming a HBEC, MCF-10F cell line, that is estrogen receptor-a (ERα) negative and ERβ positive.2-Hydroxyestradiol induces oxidative DNA damage and apoptosis in human mammary epithelial cells.
产品资料
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