产品
编 号：F338419
分子式：C15H22N2O3
分子量：278.35
分子式：C15H22N2O3
分子量：278.35
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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50mg
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结构图
CAS No: 3686-58-6
产品详情
生物活性：
Tolycaine is a local anaesthetic. Tolycaine also induces a convulsive response in experimental animals.
体内研究：
Tolycaine (140, 150 mg/kg; i.p.; single) induces convulsions by modification of monoamines in rat brain.Animal Model:Male Wistar rats (190-230 g).
Dosage:130, 140, 150, 165 mg/kg
Administration:Intraperitoneal injection; single.
Result:Produced clonic convulsions following ataxia and the loss of the righting reflex and the frequency of convulsions was dose-dependently intensified, as shown by shortening of the latency and prolongations of the duration and the sedation time.Produced a significant elevation of noradrenaline and 5-hydroxytryptamine levels in all brain regions in the convulsive state from the levels in the non-convulsive state when at 140 mg/kg.Led to rats took the opisthotonic position, gasped for breath, and died during the cdnvulsions when dosage more than 150 mg/kg.
Tolycaine is a local anaesthetic. Tolycaine also induces a convulsive response in experimental animals.
体内研究：
Tolycaine (140, 150 mg/kg; i.p.; single) induces convulsions by modification of monoamines in rat brain.Animal Model:Male Wistar rats (190-230 g).
Dosage:130, 140, 150, 165 mg/kg
Administration:Intraperitoneal injection; single.
Result:Produced clonic convulsions following ataxia and the loss of the righting reflex and the frequency of convulsions was dose-dependently intensified, as shown by shortening of the latency and prolongations of the duration and the sedation time.Produced a significant elevation of noradrenaline and 5-hydroxytryptamine levels in all brain regions in the convulsive state from the levels in the non-convulsive state when at 140 mg/kg.Led to rats took the opisthotonic position, gasped for breath, and died during the cdnvulsions when dosage more than 150 mg/kg.
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