产品
编 号：F341183
分子式：C20H26O6
分子量：362.42
分子式：C20H26O6
分子量：362.42
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CAS No: 3776-39-4
产品详情
生物活性：
Enmein is isolated from I. serra with immunosuppressive effect.
体内研究：
Enmein (inject to ear; 6.52-13.04 mg/kg; 5 days) inhibits the xylene-induced ear swelling and inhibits IL-2 expression.Animal Model:Balb/c mice
Dosage:6.52 mg/kg, 9.78 mg/kg or 13.04 mg/kg
Administration:Injected to ear; 6.52 mg/kg, 9.78 mg/kg or 13.04 mg/kg; 5 days
Result:Had inhibitory effect on IL-2 release in blood.
体外研究：
Enmein shows significant inhibitory effect toward K562 with an IC50 value ranging from 3.2 μg/ml to 8.2 μg/ml.Enmein (3.13-25 μg/ml; 48 hours) has inhibitory effect on lymphocytes with significant difference within concentration from 6.25 μg/ml to 25 μg/ml.Enmein (5.5-22 μg/ml; 48 hours) causes the percentage of S stage cells decreased from 19% to 6%, causes the percentage of G2/M stage cells to decrease from 2% to 0.4%.
Enmein is isolated from I. serra with immunosuppressive effect.
体内研究：
Enmein (inject to ear; 6.52-13.04 mg/kg; 5 days) inhibits the xylene-induced ear swelling and inhibits IL-2 expression.Animal Model:Balb/c mice
Dosage:6.52 mg/kg, 9.78 mg/kg or 13.04 mg/kg
Administration:Injected to ear; 6.52 mg/kg, 9.78 mg/kg or 13.04 mg/kg; 5 days
Result:Had inhibitory effect on IL-2 release in blood.
体外研究：
Enmein shows significant inhibitory effect toward K562 with an IC50 value ranging from 3.2 μg/ml to 8.2 μg/ml.Enmein (3.13-25 μg/ml; 48 hours) has inhibitory effect on lymphocytes with significant difference within concentration from 6.25 μg/ml to 25 μg/ml.Enmein (5.5-22 μg/ml; 48 hours) causes the percentage of S stage cells decreased from 19% to 6%, causes the percentage of G2/M stage cells to decrease from 2% to 0.4%.
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