产品
编 号:F341725
分子式:C23H38O
分子量:330.56
产品类型
结构图
CAS No: 3796-63-2
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产品详情
生物活性:
(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity. (5E,9E,13E)-Teprenone induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress.
体内研究:
(5E,9E,13E)-Teprenone induces hat sock proteins accumulations in rat gastric mucosa.Animal Model:Male Wister strain rats (≈250 g)
Dosage:200 mg/kg
Administration:Oral administration
Result:Caused accumulations of all of HSP90, HSP70, HSC70 and HSP60 within 60 minutes.
体外研究:
(5E,9E,13E)-Teprenone might transiently activate the transcription of HSP70 gene.The heat shock element–binding activity reflects the activation of heat shock factor 1 in response to (5E,9E,13E)-Teprenone.