产品
编 号：F342375
分子式：C19H12F2N4
分子量：334.32
分子式：C19H12F2N4
分子量：334.32
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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5mg
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10mg
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25mg
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50mg
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100mg
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结构图
CAS No: 381168-77-0
产品详情
生物活性：
ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization, acts as a probe molecule that has low micromolar inhibitory activity. ML367 blocks DNA repair pathways, suppresses general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation.
体外研究：
在存在或不存在 20 μM 5-FUrd的情况下，ML367 (0-40 μM，16 小时) 抑制 HEK293T 细胞中的 FLAG-ATAD5 稳定性。
ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization, acts as a probe molecule that has low micromolar inhibitory activity. ML367 blocks DNA repair pathways, suppresses general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation.
体外研究：
在存在或不存在 20 μM 5-FUrd的情况下，ML367 (0-40 μM，16 小时) 抑制 HEK293T 细胞中的 FLAG-ATAD5 稳定性。
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