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编 号：F347186
分子式：C22H36O5
分子量：380.52
分子式：C22H36O5
分子量：380.52
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CAS No: 39746-25-3
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生物活性：
16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway.
体内研究：
16,16-二甲基前列腺素 E2 (16,16-二甲基 PGE2；10 μg/kg；腹腔注射；每 12 小时一次；持续 8 天) 可挽救 Tpl2IMF-KO 小鼠恶化的 DSS 结肠炎表型和恢复上皮增殖和结构。Animal Model:Tpl2IMF-KO mice
Dosage:10 μg/kg
Administration:IP; every 12 hours; for 8 days
Result:Rescued the exacerbated DSS colitis phenotype and restores epithelial proliferation and structure.
16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway.
体内研究：
16,16-二甲基前列腺素 E2 (16,16-二甲基 PGE2；10 μg/kg；腹腔注射；每 12 小时一次；持续 8 天) 可挽救 Tpl2IMF-KO 小鼠恶化的 DSS 结肠炎表型和恢复上皮增殖和结构。Animal Model:Tpl2IMF-KO mice
Dosage:10 μg/kg
Administration:IP; every 12 hours; for 8 days
Result:Rescued the exacerbated DSS colitis phenotype and restores epithelial proliferation and structure.
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