产品
编 号：F039726
分子式：C18H17ClN2O3S
分子量：376.86
分子式：C18H17ClN2O3S
分子量：376.86
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
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10mg
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50mg
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结构图
CAS No: 1118807-13-8
产品详情
生物活性：
KY02111 is a canonical WNT signaling (β-catenin) inhibitor which promotes differentiation of hPSCs to cardiomyocytes. KY02111 can be used for the research of human cardiomyocyte regeneration.
体外研究：
KY02111 promotes differentiation by inhibiting WNT signaling in hPSCs.KY02111 induces cardiomyocytes expressed the cardiac markers, αMHC, NKH2.5, and HCN4.KY02111 (1-10 μM; 12 hours, 24 hours) reduces WNT signaling in both IMR90-1 cells and HEK293 cells in a dose-dependent manner.KY02111 treatment with WNT signaling modulators produces robust cardiac differentiation of hPSCs in a xeno-free, defined medium, devoid of serum and any kind of recombinant cytokines and hormones, such as BMP4, Activin A, or insulin.
KY02111 is a canonical WNT signaling (β-catenin) inhibitor which promotes differentiation of hPSCs to cardiomyocytes. KY02111 can be used for the research of human cardiomyocyte regeneration.
体外研究：
KY02111 promotes differentiation by inhibiting WNT signaling in hPSCs.KY02111 induces cardiomyocytes expressed the cardiac markers, αMHC, NKH2.5, and HCN4.KY02111 (1-10 μM; 12 hours, 24 hours) reduces WNT signaling in both IMR90-1 cells and HEK293 cells in a dose-dependent manner.KY02111 treatment with WNT signaling modulators produces robust cardiac differentiation of hPSCs in a xeno-free, defined medium, devoid of serum and any kind of recombinant cytokines and hormones, such as BMP4, Activin A, or insulin.
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