产品
编 号:F347778
分子式:C8H10Cl3N
分子量:226.53
产品类型
结构图
CAS No: 39959-66-5
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生物活性:
1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure.
体内研究:
1-(2,3-Dichlorophenyl)ethanamine hydrochloride (50 mg/kg; i.p. once daily for three days) effects blood pressure of spontaneously hypertensive rats .Animal Model:Adult spontaneously hypertensive rats (SHR) and Wistar Kyoto rats
Dosage:50 mg/kg
Administration:Intraperitoneal injection; 50 mg/kg; once daily, for 3 consecutive days
Result:Significantly reduced of the blood pressure in spontaneously hypertensive rats, but showed no significant changes in Wistar-Kyoto rats.