产品
编 号:F350286
分子式:C10H19N3O2
分子量:213.28
产品类型
结构图
CAS No: 40580-59-4
联系客服
产品详情
生物活性:
Guanadrel is an orally active postganglionic adrenergic inhibitor of spiroketal. Guanadre can be used in anti-hypertensive studies.
体内研究:
Guanadrel (oral gavage, 15-400 mg/kg, every day, 6-52 weeks) has little toxicity to the nervous system in rats and dogs.Animal Model:Rats, dogs
Dosage:15-400 mg/kg
Administration:Oral gavage; every day; 6-52 weeks
Result:Showed a slight increase in the weight of the prostate and adrenal glands while loss in the kidney in rats.Decreased weight gain values in a dose-dependent manner but liver function is normal in dogs.