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编 号:F350286
分子式:C10H19N3O2
分子量:213.28
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1mg
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5mg
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10mg
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25mg
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生物活性:
Guanadrel is an orally active postganglionic adrenergic inhibitor of spiroketal. Guanadre can be used in anti-hypertensive studies.

体内研究:
Guanadrel (oral gavage, 15-400 mg/kg, every day, 6-52 weeks) has little toxicity to the nervous system in rats and dogs.Animal Model:Rats, dogs
Dosage:15-400 mg/kg
Administration:Oral gavage; every day; 6-52 weeks
Result:Showed a slight increase in the weight of the prostate and adrenal glands while loss in the kidney in rats.Decreased weight gain values in a dose-dependent manner but liver function is normal in dogs.
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