产品
编 号：F356330
分子式：C22H22O10
分子量：446.4
分子式：C22H22O10
分子量：446.4
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 4291-60-5
产品详情
生物活性：
Tilianin is an active flavonoid glycoside found in many medical plants, with potential anti-hypertensive, myocardial-protective, anti-diabetic, anti-hyperlipidemic, anti-inflammatory and antioxidant effects.
体内研究：
Tilianin (10 mg/kg; i.p.) is a potential agent for ameliorating LPS-induced acute lung injury (ALI).Tilianin shows Tmax=10.8 min,Cmax=176.9 nmol/L, AUC0-∞= 17.4 min*μmol/L in mice.Animal Model:C57BL/6 mouse
Dosage:10 mg/kg
Administration:Intraperitoneal injection
Result:Attenuated infiltration of macrophages and histopathological changes and improved inflammation.
Animal Model:Male FVB mice (6-10 weeks)
Dosage:10 mg/kg (Pharmacokinetic Analysis)
Administration:Oral gavage
Result:Tmax(10.8 min), Cmax(176.9 nmol/L), AUC0-∞(17.4 min*μmol/L).
体外研究：
Tilianin (10 μM, 20 μM) reduced secretion of LPS (1 μg/mL)-induced proinflammatory cytokine in RAW264.7 macrophage cell.
Tilianin is an active flavonoid glycoside found in many medical plants, with potential anti-hypertensive, myocardial-protective, anti-diabetic, anti-hyperlipidemic, anti-inflammatory and antioxidant effects.
体内研究：
Tilianin (10 mg/kg; i.p.) is a potential agent for ameliorating LPS-induced acute lung injury (ALI).Tilianin shows Tmax=10.8 min,Cmax=176.9 nmol/L, AUC0-∞= 17.4 min*μmol/L in mice.Animal Model:C57BL/6 mouse
Dosage:10 mg/kg
Administration:Intraperitoneal injection
Result:Attenuated infiltration of macrophages and histopathological changes and improved inflammation.
Animal Model:Male FVB mice (6-10 weeks)
Dosage:10 mg/kg (Pharmacokinetic Analysis)
Administration:Oral gavage
Result:Tmax(10.8 min), Cmax(176.9 nmol/L), AUC0-∞(17.4 min*μmol/L).
体外研究：
Tilianin (10 μM, 20 μM) reduced secretion of LPS (1 μg/mL)-induced proinflammatory cytokine in RAW264.7 macrophage cell.
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