产品
编 号:F357963
分子式:C21H16O7
分子量:380.35
产品类型
结构图
CAS No: 4366-18-1
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生物活性:
Coumetarol (Dicumoxane) is a vitamin K antagonist.
体外研究:
Coumetarol (Dicumoxane), an oral anticoagulant, is active in both models. The vitamin K antagonist Coumetarol is effective in both models after oral treatment but inhibits the thrombus formation more strongly in the arterio-venous shunt model. Treatment with the vitamin K antagonist Coumetarol in a dose of 25 mg/kg p.o. twice daily for 2 days results in a significant reduction in thrombus weight by 50% in the venous stasis model and by 75% in the arterio-venous shunt model. In both experiments the coagulation time as measured by the Thrombotest is prolonged to the same extent.