产品
编 号：F358129
分子式：C19H26N6O6
分子量：434.45
分子式：C19H26N6O6
分子量：434.45
产品类型
规格
价格
是否有货
50mg
询价
询价
100mg
询价
询价
250mg
询价
询价
500mg
询价
询价
结构图
CAS No: 437-74-1
产品详情
生物活性：
Xanthinol Nicotinate (Xanthinol Niacinate), a vasodilator, can act directly on the smooth muscle of small arteries and capillaries. Xanthinol Nicotinate expands blood vessels, improves blood rheology and reduces peripheral vascular resistance.
体内研究：
Xanthinol Nicotinate (Xanthinol Niacinate; 75 mg/kg; IP) rapidly and transiently modifies tumor pO2 and the maximal pO2 values are obtained 10 to 30 minutes after Xanthinol Nicotinate administration. Xanthinol Nicotinate is able to radiosensitize the tumors when applying 10 Gy of X-Rays during the reoxygenation of the tumors (enhancement in radiation response of 1.4). Animal Model:5 week-old male NMRI mice
Dosage:75 mg/kg
Administration:IP
Result:Rapidly and transiently modified tumor pO2 and Maximal pO2 values were obtained 10 to 30 minutes after XN administration.
体外研究：
Xanthinol Nicotinate (Xanthinol Niacinate; 2.76-276 μM; for 24 hours) inhibits HUASMC proliferation in a dose-dependent manner. Xanthinol Nicotinate (2.76-276 μM; for 24 hours) dose-dependently decreases the PDGFR mRNA and PDGFR-β levels on the cell membranes of HUASMCs.
Xanthinol Nicotinate (Xanthinol Niacinate), a vasodilator, can act directly on the smooth muscle of small arteries and capillaries. Xanthinol Nicotinate expands blood vessels, improves blood rheology and reduces peripheral vascular resistance.
体内研究：
Xanthinol Nicotinate (Xanthinol Niacinate; 75 mg/kg; IP) rapidly and transiently modifies tumor pO2 and the maximal pO2 values are obtained 10 to 30 minutes after Xanthinol Nicotinate administration. Xanthinol Nicotinate is able to radiosensitize the tumors when applying 10 Gy of X-Rays during the reoxygenation of the tumors (enhancement in radiation response of 1.4). Animal Model:5 week-old male NMRI mice
Dosage:75 mg/kg
Administration:IP
Result:Rapidly and transiently modified tumor pO2 and Maximal pO2 values were obtained 10 to 30 minutes after XN administration.
体外研究：
Xanthinol Nicotinate (Xanthinol Niacinate; 2.76-276 μM; for 24 hours) inhibits HUASMC proliferation in a dose-dependent manner. Xanthinol Nicotinate (2.76-276 μM; for 24 hours) dose-dependently decreases the PDGFR mRNA and PDGFR-β levels on the cell membranes of HUASMCs.
产品资料
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