产品
编 号：F370251
分子式：C8H10N2O4
分子量：198.18
分子式：C8H10N2O4
分子量：198.18
产品类型
规格
价格
是否有货
25mg
询价
询价
50mg
询价
询价
结构图
CAS No: 500-44-7
产品详情
生物活性：
Mimosine, a tyrosine analog , can act as an antioxidant by its potent iron-binding activity. Mimosine is a known chelator of Fe(III). Mimosine induces apoptosis through metal ion chelation, mitochondrial activation and ROS production in human leukemic cells. Anti-cancer, antiinflammation.
体内研究：
Mimosine (30, and 60 mg/kg) decreases sperm concentration.Animal Model:ICR male mice (6-8 weeks)
Dosage:15, 30, or 60 mg/kg
Administration:Injected (i.p.) for 7 consecutive days
Result:Could significantly reduce sperm concentration as compared to the control or low dose mimosine group (15 mg/kg) at doses of 30 and 60 mg/kg.
体外研究：
Mimosine, a known chelator of Fe(III), may facilitate Fe(III) uptake in leucaena by serving as a phytosiderophore. Mimosine, a bidentate iron-binding ligand, may also play a role in cellular translocation of iron within leucaena.Mimosine is a toxic nonprotein amino acid that is a major constituent of the tropical legumesLeucaenaandMimosa.Mimosine (400 μM), through iron chelation, reversibly blocks cell cycle progression in MDA-MB-453 human breast cancer cells.Mimosine (400 μM) reduces DNA synthesis by greater than 90% of control within 4 hr of treatment, and suppresses total proline-directed protein kinase activity to less than 10% of control after 16 hr treatment.
Mimosine, a tyrosine analog , can act as an antioxidant by its potent iron-binding activity. Mimosine is a known chelator of Fe(III). Mimosine induces apoptosis through metal ion chelation, mitochondrial activation and ROS production in human leukemic cells. Anti-cancer, antiinflammation.
体内研究：
Mimosine (30, and 60 mg/kg) decreases sperm concentration.Animal Model:ICR male mice (6-8 weeks)
Dosage:15, 30, or 60 mg/kg
Administration:Injected (i.p.) for 7 consecutive days
Result:Could significantly reduce sperm concentration as compared to the control or low dose mimosine group (15 mg/kg) at doses of 30 and 60 mg/kg.
体外研究：
Mimosine, a known chelator of Fe(III), may facilitate Fe(III) uptake in leucaena by serving as a phytosiderophore. Mimosine, a bidentate iron-binding ligand, may also play a role in cellular translocation of iron within leucaena.Mimosine is a toxic nonprotein amino acid that is a major constituent of the tropical legumesLeucaenaandMimosa.Mimosine (400 μM), through iron chelation, reversibly blocks cell cycle progression in MDA-MB-453 human breast cancer cells.Mimosine (400 μM) reduces DNA synthesis by greater than 90% of control within 4 hr of treatment, and suppresses total proline-directed protein kinase activity to less than 10% of control after 16 hr treatment.
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