产品
编 号:F041841
分子式:C31H33N5O2S
分子量:539.69
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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50mg
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生物活性:
Amcasertib (BBI503) is an orally active and small-molecule multi-kinase inhibitor. Amcasertib exhibits inhibitory activity against the NANOG and CD133 expression and cell viability in PC-9/GR cells. As an orally available cancer cell stemness kinase inhibitor with potential antineoplastic activity, it is currently being studied in phase I clinical trials in a number of cancers.

体外研究:
Amcasertib (0-1μM; 48h) inhibits the NANOG and CD133 expression in PC-9/GR cells. Amcasertib also significantly suppresses the growth of PC-9/GR cells in a dose-dependent manner.
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