产品
编 号：F374111
分子式：C16H17BrN2S
分子量：349.29
分子式：C16H17BrN2S
分子量：349.29
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
440
In-stock
10mg
752
In-stock
25mg
1675
In-stock
50mg
2931
In-stock
100mg
4103
In-stock
结构图
CAS No: 511296-88-1
产品详情
生物活性：
Pifithrin-β hydrobromide (PFT β hydrobromide) is a potent p53 inhibitor with an IC50 of 23 μM.
体外研究：
Pifithrin-α hydrobromide (PFT β hydrobromide), an inhibitor of the p53 protein, is regarded as a lead compound for cancer and neurodegenerative disease therapy. Pifithrin-α is very unstable in culture medium and rapidly converts to its condensation product pifithrin-β, the N-acetyl derivative. After 24 h, the viability assay shows that the pretreatments with 1 and 10 μM pifithrin-β exerts neuroprotective effects.
Pifithrin-β hydrobromide (PFT β hydrobromide) is a potent p53 inhibitor with an IC50 of 23 μM.
体外研究：
Pifithrin-α hydrobromide (PFT β hydrobromide), an inhibitor of the p53 protein, is regarded as a lead compound for cancer and neurodegenerative disease therapy. Pifithrin-α is very unstable in culture medium and rapidly converts to its condensation product pifithrin-β, the N-acetyl derivative. After 24 h, the viability assay shows that the pretreatments with 1 and 10 μM pifithrin-β exerts neuroprotective effects.
产品资料
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