产品
编 号：F004880
分子式：C18H20FN3O4
分子量：361.37
分子式：C18H20FN3O4
分子量：361.37
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
400
In-stock
5g
760
In-stock
结构图
CAS No: 100986-85-4
产品详情
生物活性：
Levofloxacin ((-)-Ofloxacin) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin inhibits the DNA gyrase and topoisomerase IV. Levofloxacin can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin shows anti-orthopoxvirus activity.
体内研究：
Levofloxacin (10.7 mg/kg；腹腔注射，每天一次，持续 10 天或 3 周) 时间依赖性地诱导白化小鼠肝脏和心脏的毒性作用。Animal Model:Matured male Albino mice
Dosage:10.7 mg/kg
Administration:Intraperitoneal injection; 10.7 mg/kg, once daily for 10 days or 3 weeks.
Result:Induced severe congestion of blood vessels in the portal area, central veins with inflammatory cells infiltration, necrosis with pyknosis of cardiac muscle nuclei and apoptosis, degeneration and necrosis of hepatocytes.
体外研究：
左氧氟沙星对结核分枝杆菌敏感菌株 OFLO、LVFX 和 SPFX 的 MIC50 值分别为 1.0、0.5 和 0.25 μg/mL。
Levofloxacin ((-)-Ofloxacin) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin inhibits the DNA gyrase and topoisomerase IV. Levofloxacin can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin shows anti-orthopoxvirus activity.
体内研究：
Levofloxacin (10.7 mg/kg；腹腔注射，每天一次，持续 10 天或 3 周) 时间依赖性地诱导白化小鼠肝脏和心脏的毒性作用。Animal Model:Matured male Albino mice
Dosage:10.7 mg/kg
Administration:Intraperitoneal injection; 10.7 mg/kg, once daily for 10 days or 3 weeks.
Result:Induced severe congestion of blood vessels in the portal area, central veins with inflammatory cells infiltration, necrosis with pyknosis of cardiac muscle nuclei and apoptosis, degeneration and necrosis of hepatocytes.
体外研究：
左氧氟沙星对结核分枝杆菌敏感菌株 OFLO、LVFX 和 SPFX 的 MIC50 值分别为 1.0、0.5 和 0.25 μg/mL。
产品资料
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