产品
编 号：F391747
分子式：C20H24N2O2
分子量：324.42
分子式：C20H24N2O2
分子量：324.42
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
400
In-stock
结构图
CAS No: 56-54-2
产品详情
生物活性：
Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. Quinidine is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine is also a K+ channel blocker with an IC50 of 19.9 μM, and can induce apoptosis. Quinidine can be used for malaria research.
体内研究：
Quinidine 对 PTZ 诱导的癫痫发作阈值有影响。Animal Model:Male mice of the NMRI strain (age 5-6 weeks and weight 25-30 g)[5
Dosage:10, 20, and 30 mg/kg
Administration:Intraperitoneal injection; 10, 20, and 30 mg/kg; once
Result:Increased the threshold dose for the onset to tonic hind limb extension at a dose of 30 mg/kg, compared to the saline-treated control group (p<0.05).
体外研究：
Quinidine 对 MES-SA 细胞具有细胞毒性，可诱导细胞凋亡。
Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. Quinidine is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine is also a K+ channel blocker with an IC50 of 19.9 μM, and can induce apoptosis. Quinidine can be used for malaria research.
体内研究：
Quinidine 对 PTZ 诱导的癫痫发作阈值有影响。Animal Model:Male mice of the NMRI strain (age 5-6 weeks and weight 25-30 g)[5
Dosage:10, 20, and 30 mg/kg
Administration:Intraperitoneal injection; 10, 20, and 30 mg/kg; once
Result:Increased the threshold dose for the onset to tonic hind limb extension at a dose of 30 mg/kg, compared to the saline-treated control group (p<0.05).
体外研究：
Quinidine 对 MES-SA 细胞具有细胞毒性，可诱导细胞凋亡。
产品资料
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