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编 号：F392645
分子式：C63H107N23O16S
分子量：1474.73
分子式：C63H107N23O16S
分子量：1474.73
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CAS No: 568565-11-7
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生物活性：
(Ala13)-Apelin-13 is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 inhibits gastric motility through vagal cholinergic pathway.
体内研究：
(Ala13)-Apelin-13 (1-300 pmol/60 nl；显微注射到 DVC 中) 以剂量依赖性方式降低大鼠的胃张力和胃动力。Animal Model:250-300 g, Sprague-Dawley rats
Dosage:1-300 pmol/60 nl
Administration:Microinjected into the DVC (dorsal vagal complex (DVC)
Result:Decreased gastric tone and motility in a dose-dependent manner with D50?≈?27 pmol for both antrum and corpus.
(Ala13)-Apelin-13 is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 inhibits gastric motility through vagal cholinergic pathway.
体内研究：
(Ala13)-Apelin-13 (1-300 pmol/60 nl；显微注射到 DVC 中) 以剂量依赖性方式降低大鼠的胃张力和胃动力。Animal Model:250-300 g, Sprague-Dawley rats
Dosage:1-300 pmol/60 nl
Administration:Microinjected into the DVC (dorsal vagal complex (DVC)
Result:Decreased gastric tone and motility in a dose-dependent manner with D50?≈?27 pmol for both antrum and corpus.
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