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编 号:F393194
分子式:C14H14N2O2
分子量:242.27
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生物活性:
Isonixin (Isonixine) is a non-steroidal compound. Isonixin can be used for the research of pain and inflammation.

体内研究:
Isonixine potentiates hexobarbital sleep time, reduces motor activity, antagonizes cardiazol-induced convulsions, causes hyperthermia, and inhibits tremorine-induced trembling in mice.Isonixine (p.o.) showes a 3.15 h half-life of absorption and rapidly absorbs in a gastro-intestinal tract.Isonixine (i.v., intragastrically and intraduodenally) mainly excrets via urine, and isonixine can be eliminated by urine within 50 hours.Isonixine (2000 mg/kg; p.o. once daily for 6 months) presents some mild toxic effects and induces no gastrointestinal lesion in male rabbits and rats.
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