产品
编 号:F395046
分子式:C7H10N4O2S
分子量:214.24
产品类型
结构图
CAS No: 57-67-0
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产品详情
生物活性:
Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery.
体内研究:
Sulfaguanidine (2.5 mg/kg; i.v.) exhibits CLt (adult 0.29, neonate 0.14 L/h/kg), AUC0-∞ (adult 8.18, neonate 20.46 μg?h/mL), and Vdss (adult 0.65, neonate 0.59 L/kg) in rats.Sulfaguanidine (2.5 mg/kg; p.o.) exhibits absolute bioavailability (adult 12.76%, neonate 57.86%), Cmax (adult 0.41, neonate 3.56 μg/mL), and Tmax (adult 1.67, neonate 1.50 h) in rats.