产品
编 号:F395190
分子式:C32H44O14
分子量:652.68
产品类型
结构图
CAS No: 57710-64-2
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产品详情
生物活性:
Crocin IV (Dicrocin), a crocetin glycoside, is a carotenoid pigment. Crocin IV has potent antioxidant activity.
体外研究:
Crocin IV (Dicrocin; 10 μM; 24 hours) has little or no effect on the prolongation of cell survival in PC12 cell. Crocin IV enhances γ-GCS mRNA expression in serum-deprived and hypoxic PC12 cells. Measurements of cell viability, peroxidized membrane lipids and caspase-3 activity showed that the rank order of the neuroprotective potency at a concentration of 10 μM is crocin>tricrocin>dicrocin and picrocrocin (the latter two crocins had a little or no potency).