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编 号:F395385
分子式:C12H24N2O9
分子量:340.33
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生物活性:
Chitobiose, a chitosan oligosaccharide, is a dimer of β-1,4-linked glucosamine units. Chitobiose has orally activity and high antioxidant activity.

体内研究:
Chitobiose (30, 100, 300 mg/kg; p.o., single) can enters the circulatory system when given orally.Pharmacokinetic Parameters of Chitobiose in Wistar strain male rats.PO (30 mg/kg) PO (100 mg/kg)PO (300 mg/kg)
Tmax (h)0.91.01.8
Cpmax (μg/mL)1.14.46.9
AUC0-4h (μg·h/mL)2.59.017.6
AUMC0-4h (μg·h^2/mL)4.013.235.6
MRT (h)1.61.51.6
MAT (h)1.11.01.2
ka (h^-1)0.950.990.96
F1-4h (%)1.82.01.3
Animal Model:Wistar strain male rats (7 weeks, 165-185 g)
Dosage:30, 100, 300 mg/kg
Administration:p.o., single (Pharmacokinetics analysis)
Result:Entered the circulatory system when given orally.
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