产品
编 号：F395983
分子式：C16H20N4O6
分子量：364.35
分子式：C16H20N4O6
分子量：364.35
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CAS No: 57998-68-2
产品详情
生物活性：
Diaziquone (Diaziquone) is a water-soluble, synthetic aziridinylbenzoquinone with potential antineoplastic activity.
体内研究：
Diaziquone (6.75mg /sq m daily for 5 consecutive days or single-dose 26 mg/sq m) has a broad range of activity of diaziquone against primary nervous system tumors and has enhancement effect combined with either 1,3-bis(2-chloroethyl)-1-nitrosourea or procarbazine in athymic mice.Animal Model:Homozygous nu/nu BALB/c athymic mice
Dosage:6.75mg /sq m or 26 mg/sq m
Administration:6.75mg /sq m daily for 5 consecutive days or single-dose 26 mg/sq m
Result:Showed rapid clearance in the plasma of athymic mice with a half-life of approximately 11.5 min.Produced significant growth delays.Produced significant increases in the median growth delay, significant increases in the number of tumor regressions.
Diaziquone (Diaziquone) is a water-soluble, synthetic aziridinylbenzoquinone with potential antineoplastic activity.
体内研究：
Diaziquone (6.75mg /sq m daily for 5 consecutive days or single-dose 26 mg/sq m) has a broad range of activity of diaziquone against primary nervous system tumors and has enhancement effect combined with either 1,3-bis(2-chloroethyl)-1-nitrosourea or procarbazine in athymic mice.Animal Model:Homozygous nu/nu BALB/c athymic mice
Dosage:6.75mg /sq m or 26 mg/sq m
Administration:6.75mg /sq m daily for 5 consecutive days or single-dose 26 mg/sq m
Result:Showed rapid clearance in the plasma of athymic mice with a half-life of approximately 11.5 min.Produced significant growth delays.Produced significant increases in the median growth delay, significant increases in the number of tumor regressions.
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