产品
编 号：F398193
分子式：C30H38O11
分子量：574.62
分子式：C30H38O11
分子量：574.62
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
询价
10mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 58812-37-6
产品详情
生物活性：
Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities.
体内研究：
Toosendanin (0.5 and 1 mg/kg, Intraperitoneal injection daily for 7 days) alleviates DSS-induced experimental colitis by inhibiting M1 macrophage polarization and regulating NLRP3 inflammasome and Nrf2/HO-1 signaling, and may provide a novel Chinese patent medicine for the treatment of murine colitis.Animal Model:Forty-eight male C57BL/6 mice weighing 20-22 g.
Dosage:0.5 and 1 mg/kg.
Administration:Intraperitoneal injection daily for 7 days.
Result:Protected against DSS-induced colitis in mice.Inhibited the expression of proinflammatory cytokines in DSS-induced UC and improved oxidative stress.
Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities.
体内研究：
Toosendanin (0.5 and 1 mg/kg, Intraperitoneal injection daily for 7 days) alleviates DSS-induced experimental colitis by inhibiting M1 macrophage polarization and regulating NLRP3 inflammasome and Nrf2/HO-1 signaling, and may provide a novel Chinese patent medicine for the treatment of murine colitis.Animal Model:Forty-eight male C57BL/6 mice weighing 20-22 g.
Dosage:0.5 and 1 mg/kg.
Administration:Intraperitoneal injection daily for 7 days.
Result:Protected against DSS-induced colitis in mice.Inhibited the expression of proinflammatory cytokines in DSS-induced UC and improved oxidative stress.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备