产品
编 号：F399095
分子式：C49H75N13O12
分子量：1038.2
分子式：C49H75N13O12
分子量：1038.2
产品类型
规格
价格
是否有货
100μg
询价
询价
结构图
CAS No: 111755-37-4
产品详情
生物活性：
Microcystin-RR (Cyanoviridin RR) is a potent and orally active protein phosphatase inhibitor. Microcystin-RR induces Apoptosis and ER stress in mice liver.
体内研究：
Microcystin-RR (0、4..6、23、46、93、186 μg/mL；灌胃；每日一次，连续 7 天) 在小鼠肝脏中以剂量依赖性方式诱导细胞凋亡并增加 Bax、p53 的表达，降低 Bcl-2 的表达。Animal Model:20-22 g, male ICR mice
Dosage:0, 4..6, 23, 46, 93, 186 μg/mL
Administration:Gavage; daily for 7 days
Result:Induced obvious apoptosis in mice liver with the percentage of apoptotic cells were 10.46, 12.6, 12.7, 13.3, 28.5, and 37.5% for 0, 4..6, 23, 46, 93, 186 μg/mL, respectively; increased the expression of Bax,p53, decreased the expression of Bcl-2 in a dose-dependent manner in mice liver.
Microcystin-RR (Cyanoviridin RR) is a potent and orally active protein phosphatase inhibitor. Microcystin-RR induces Apoptosis and ER stress in mice liver.
体内研究：
Microcystin-RR (0、4..6、23、46、93、186 μg/mL；灌胃；每日一次，连续 7 天) 在小鼠肝脏中以剂量依赖性方式诱导细胞凋亡并增加 Bax、p53 的表达，降低 Bcl-2 的表达。Animal Model:20-22 g, male ICR mice
Dosage:0, 4..6, 23, 46, 93, 186 μg/mL
Administration:Gavage; daily for 7 days
Result:Induced obvious apoptosis in mice liver with the percentage of apoptotic cells were 10.46, 12.6, 12.7, 13.3, 28.5, and 37.5% for 0, 4..6, 23, 46, 93, 186 μg/mL, respectively; increased the expression of Bax,p53, decreased the expression of Bcl-2 in a dose-dependent manner in mice liver.
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