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编 号:F399824
分子式:C16H20ClN3
分子量:289.8
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生物活性:
Chloropyramine is competitive reversible H1 receptor antagonist. Chloropyramine also has anti-tumour activity in breast cancer. Chloropyramine can be used for the research of allergic conditions, such as conjunctivitis and bronchial asthma.

体内研究:
Chloropyramine (i.p.; 10 mg/kg) abolishes hypothermia in rats.Animal Model:Rats
Dosage:10 mg/kg
Administration:Intraperitoneal
Result:Reduced histamine-induced hypothermia.

体外研究:
Chloropyramine (25, 50 μM; 24 h, 48 h) induces SASH1 expression and apoptosis in breast cancer cell lines.
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