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编 号:F400336
分子式:C3H8OS2
分子量:124.23
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100mg
400
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生物活性:
Dimercaprol (2,3-Dimercapto-1-propanol) is an anti-heavy metal-poisoning agent, which exhibits anti-HIV activity. Dimercaprol can be used for the study for arsenic, mercury, gold, lead, antimony, and other toxic metal poisoning.

体内研究:
Dimercaprol(2,3-Dimercapto-1-propanol;12.5-75 mg/kg;皮下注射;一次)会增加死亡率并降低肝脏和肾脏中的汞含量。Animal Model:Wistar rats (13 days old) injected with HgCl2
Dosage:12.5 mg/kg, 25 mg/kg, 50 mg/kg or 75 mg/kg
Administration:Subcutaneous injection; once
Result:Decreased the mercury contents in liver and kidney.

体外研究:
Dimercaprol(10-100 μM;4 小时)可以以剂量依赖性方式显着保护 PC-12 细胞免受丙烯醛介导的细胞死亡。
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