产品
编 号：F401413
分子式：C16H15ClN6O3
分子量：374.78
分子式：C16H15ClN6O3
分子量：374.78
产品类型
规格
价格
是否有货
结构图
CAS No: 59878-63-6
产品详情
生物活性：
Norzopiclone is the inactive metabolite of Zopiclone. Norzopiclone has some anxiolytic properties.
体内研究：
A demethylation metabolic pathway produces Norzopiclone (N-desmethylzopiclone), a metabolite which reportedly accounts for 15% of an oral dose of racemic Zopiclone, and which is also reportedly inactive. N-oxide-Zopiclone has a similar t1/2 compared to parent Zopiclone, while the t1/2 of Norzopiclone (N-desmethyl-Zopiclone) ranges from 7 to 11 h.
体外研究：
The main urine metabolites of racemic zopiclone are the less active eszopiclone-N-oxide (RP 29753) and the inactive Norzopiclone (N-desmethyleszopiclone, RP 32273). Zopiclone has two major metabolites, N-oxideZopiclone and Norzopiclone (N-desmethyl-Zopiclone). N-oxideZopiclone has a hypnotic activity lower than the parent Zopiclone, whereas Norzopiclone (N-desmethyl-Zopiclone) lacks hypnotic effect, but has some anxiolytic properties.
Norzopiclone is the inactive metabolite of Zopiclone. Norzopiclone has some anxiolytic properties.
体内研究：
A demethylation metabolic pathway produces Norzopiclone (N-desmethylzopiclone), a metabolite which reportedly accounts for 15% of an oral dose of racemic Zopiclone, and which is also reportedly inactive. N-oxide-Zopiclone has a similar t1/2 compared to parent Zopiclone, while the t1/2 of Norzopiclone (N-desmethyl-Zopiclone) ranges from 7 to 11 h.
体外研究：
The main urine metabolites of racemic zopiclone are the less active eszopiclone-N-oxide (RP 29753) and the inactive Norzopiclone (N-desmethyleszopiclone, RP 32273). Zopiclone has two major metabolites, N-oxideZopiclone and Norzopiclone (N-desmethyl-Zopiclone). N-oxideZopiclone has a hypnotic activity lower than the parent Zopiclone, whereas Norzopiclone (N-desmethyl-Zopiclone) lacks hypnotic effect, but has some anxiolytic properties.
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