产品
编 号：F403073
分子式：C16H16N2S
分子量：268.38
分子式：C16H16N2S
分子量：268.38
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CAS No: 60477-34-1
产品详情
生物活性：
Pifithrin-β (PFT β) is a potent p53 inhibitor with an IC50 of 23 μM.
体外研究：
Pifithrin-α, an inhibitor of the p53 protein, is regarded as a lead compound for cancer and neurodegenerative disease therapy. Pifithrin-α is very unstable in culture medium and rapidly converts to its condensation product pifithrin-β (PFT β), the N-acetyl derivative. After 24 h, the viability assay shows that the pretreatments with 1 and 10 μM pifithrin-β exerts neuroprotective effects.
Pifithrin-β (PFT β) is a potent p53 inhibitor with an IC50 of 23 μM.
体外研究：
Pifithrin-α, an inhibitor of the p53 protein, is regarded as a lead compound for cancer and neurodegenerative disease therapy. Pifithrin-α is very unstable in culture medium and rapidly converts to its condensation product pifithrin-β (PFT β), the N-acetyl derivative. After 24 h, the viability assay shows that the pretreatments with 1 and 10 μM pifithrin-β exerts neuroprotective effects.
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