产品
编 号：F403437
分子式：C22H34O2
分子量：330.5
分子式：C22H34O2
分子量：330.5
产品类型
规格
价格
是否有货
结构图
CAS No: 60607-35-4
产品详情
生物活性：
Topterone is a topical antiandrogen.
体内研究：
Topterone, is administered parenterally or topically to rats, rabbits or hamsters to determine its endocrine profile. Systemic administration demonstrates that Topterone is both antiandrogenic and progestational. Topical application fails to elicit a systemic antiandrogenic response at 1 g/kg/day and only a minimal progestational response is seen at 32 mg/kg/day. No other endocrine activities are detected. Topterone inhibits stimulation of flank organ development of castrated immature male hamsters by both testosterone and dihydrotestosterone, whereas Progesterone inhibits the stimulation by only testosterone. Topical application of Topterone, has been shown to cause a regression in the development of the flank organ.
Topterone is a topical antiandrogen.
体内研究：
Topterone, is administered parenterally or topically to rats, rabbits or hamsters to determine its endocrine profile. Systemic administration demonstrates that Topterone is both antiandrogenic and progestational. Topical application fails to elicit a systemic antiandrogenic response at 1 g/kg/day and only a minimal progestational response is seen at 32 mg/kg/day. No other endocrine activities are detected. Topterone inhibits stimulation of flank organ development of castrated immature male hamsters by both testosterone and dihydrotestosterone, whereas Progesterone inhibits the stimulation by only testosterone. Topical application of Topterone, has been shown to cause a regression in the development of the flank organ.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备