产品
编 号：F403649
分子式：C5H13N2O4P
分子量：196.14
分子式：C5H13N2O4P
分子量：196.14
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 60668-24-8
产品详情
生物活性：
Alafosfalin is an inhibitor of cell wall biosynthesis. Alafosfalin is a phosphonodipeptide with antibacterial properties.
体内研究：
After s.c. administration to rats, Alafosfalin is rapidly absorbed with half-lives (t1/2) of approximately 20 minutes.Animal Model:Pairs of male SpragueDawley rats (250 to 350 g)
Dosage:20, 100, and 500 mg/ kg (single doses) or 800 mg/kg per day for 14 days (Pharmacokinetic Analysis)
Administration:Administrated by s.c.
Result:Rapidly absorbed; peak concentrations were found within 20 minutes of dosing with half-lives of approximately 20 minutes.
体外研究：
Alafosfalin is highly active against Escherichia coli and moderately active against Serratia, Klebsiella, Enterobacter, and Citrobacter, but less active against gram-positive organisms than were beta-lactams such as cephazolin or ampicillin and inactive against indole-positive Proteus, Pseudomonas, and Acinetobacter.
Alafosfalin is an inhibitor of cell wall biosynthesis. Alafosfalin is a phosphonodipeptide with antibacterial properties.
体内研究：
After s.c. administration to rats, Alafosfalin is rapidly absorbed with half-lives (t1/2) of approximately 20 minutes.Animal Model:Pairs of male SpragueDawley rats (250 to 350 g)
Dosage:20, 100, and 500 mg/ kg (single doses) or 800 mg/kg per day for 14 days (Pharmacokinetic Analysis)
Administration:Administrated by s.c.
Result:Rapidly absorbed; peak concentrations were found within 20 minutes of dosing with half-lives of approximately 20 minutes.
体外研究：
Alafosfalin is highly active against Escherichia coli and moderately active against Serratia, Klebsiella, Enterobacter, and Citrobacter, but less active against gram-positive organisms than were beta-lactams such as cephazolin or ampicillin and inactive against indole-positive Proteus, Pseudomonas, and Acinetobacter.
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