产品
编 号：F410149
分子式：C18H16FN3O2
分子量：325.34
分子式：C18H16FN3O2
分子量：325.34
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
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5mg
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10mg
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结构图
CAS No: 627518-40-5
产品详情
生物活性：
JNJ-10198409 is a relatively selective, orally active, and ATP competitive PDGF-RTK (platelet-derived growth factor receptor tyrosine kinase) inhibitor (IC50=2 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent. JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM).
体外研究：
JNJ-10198409 has potent antiproliferative activity in six of eight human tumor cell lines (IC50JNJ-10198409 相关抗体:
JNJ-10198409 is a relatively selective, orally active, and ATP competitive PDGF-RTK (platelet-derived growth factor receptor tyrosine kinase) inhibitor (IC50=2 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent. JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM).
体外研究：
JNJ-10198409 has potent antiproliferative activity in six of eight human tumor cell lines (IC50JNJ-10198409 相关抗体:
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