产品
编 号:F411056
分子式:C28H58
分子量:394.76
产品类型
结构图
CAS No: 630-02-4
联系客服
产品详情
生物活性:
Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l.
体内研究:
Octacosane (500 μg; injected at peripheral sites in relation to the original cell grafting; daily; 35 days) results in a significant delay of tumor progression with a significant antitumor effect.Animal Model:C57Bl/6 mice?with B16F10-Nex2 Cellsl
Dosage:500 μg
Administration:Injected at peripheral sites in relation to the original cell grafting; daily; 35 days
Result:Resulted in a significant delay of tumor progression with a significant antitumor effect. The survival rate of treated groups was significantly increased.
体外研究:
Octacosane (12.5-100 μg/ml; 18 h) displays strong cytotoxic activity on B16F10-Nex2 cells, with an IC50 value of 41.08 μg/ml.