产品
编 号：F412772
分子式：C24H29BrFNO3
分子量：478.39
分子式：C24H29BrFNO3
分子量：478.39
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CAS No: 63516-07-4
产品详情
生物活性：
Flutropium bromide (Ba 598Br) is a organic bromide salt of flutropium. Flutropium bromide shows an anticholinergic effect. Flutropium bromide effectively suppresses spasms and it can be used for the research of asthma and chronic obstructive pulmonary disease.
体内研究：
Flutropium bromide (0.0003%; single inhalation) inhibits the acetylcholine induced bronchoconstriction without changing the fall in blood pressure in guinea pigs.Flutropium bromide (3 and 10 mg/kg; i.v.) shows a weak mast cell stabilizing action, but no antagonistic action against LTD4 and serotonin.Animal Model:Guinea pigs
Dosage:3 and 10 mg/kg
Administration:Intravenous injection; 3 and 10 mg/kg once
Result:Showed an inhibitory action on the 48 hours homologous PCA and inhibited the release of histamine from isolated rat mast cells stimulated by antigen in guinea pigs.
体外研究：
Flutropium bromide is more effective than atropine in vitro experiments.
Flutropium bromide (Ba 598Br) is a organic bromide salt of flutropium. Flutropium bromide shows an anticholinergic effect. Flutropium bromide effectively suppresses spasms and it can be used for the research of asthma and chronic obstructive pulmonary disease.
体内研究：
Flutropium bromide (0.0003%; single inhalation) inhibits the acetylcholine induced bronchoconstriction without changing the fall in blood pressure in guinea pigs.Flutropium bromide (3 and 10 mg/kg; i.v.) shows a weak mast cell stabilizing action, but no antagonistic action against LTD4 and serotonin.Animal Model:Guinea pigs
Dosage:3 and 10 mg/kg
Administration:Intravenous injection; 3 and 10 mg/kg once
Result:Showed an inhibitory action on the 48 hours homologous PCA and inhibited the release of histamine from isolated rat mast cells stimulated by antigen in guinea pigs.
体外研究：
Flutropium bromide is more effective than atropine in vitro experiments.
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