产品
编 号：F413231
分子式：C14H10O2S
分子量：242.29
分子式：C14H10O2S
分子量：242.29
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 63676-22-2
产品详情
生物活性：
Estrogen receptor modulator 1 (compound 18) is an orally active and selective estrogen receptor modulator (SERM), with a pIC50 of 0.46. Estrogen receptor modulator 1 induces regression of Tamoxifen-resistant, hormone independent xenograft tumors.
体内研究：
Estrogen receptor modulator 1 (1.5 mg/animal; p.o. ; daily for 2 weeks) results in regression of T47D:A18/PKCα tumors.Animal Model:4-6 week old athymic mice (Harlan-Sprague-Dawley)
Dosage:1.5 mg/animal
Administration:p.o. ; daily for 2 weeks
Result:Significantly reduced tumor volume.
体外研究：
Estrogen receptor modulator 1 (compound 18) (100 nM; 10 days)inhibits T47D:A18/PKCα and T47D:A18-TAM1 colony formation.Estrogen receptor modulator 1 (100 nM; 9 days) significantly inhibits the growth of MCF-7:5C cell, and induces apoptosis in these cells 6 days.
Estrogen receptor modulator 1 (compound 18) is an orally active and selective estrogen receptor modulator (SERM), with a pIC50 of 0.46. Estrogen receptor modulator 1 induces regression of Tamoxifen-resistant, hormone independent xenograft tumors.
体内研究：
Estrogen receptor modulator 1 (1.5 mg/animal; p.o. ; daily for 2 weeks) results in regression of T47D:A18/PKCα tumors.Animal Model:4-6 week old athymic mice (Harlan-Sprague-Dawley)
Dosage:1.5 mg/animal
Administration:p.o. ; daily for 2 weeks
Result:Significantly reduced tumor volume.
体外研究：
Estrogen receptor modulator 1 (compound 18) (100 nM; 10 days)inhibits T47D:A18/PKCα and T47D:A18-TAM1 colony formation.Estrogen receptor modulator 1 (100 nM; 9 days) significantly inhibits the growth of MCF-7:5C cell, and induces apoptosis in these cells 6 days.
产品资料
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