产品
编 号：F413674
分子式：C22H21ClN2O3
分子量：396.87
分子式：C22H21ClN2O3
分子量：396.87
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
询价
10mg
询价
询价
50mg
询价
询价
结构图
CAS No: 638156-11-3
产品详情
生物活性：
CID 2011756 is an ATP competitive PKD inhibitor, with an IC50 of 3.2 μM for PKD1 in cell free assay, and also shows cellular pan-PKD inhibitory activity against PKD2 and PKD3 (IC50, 0.6 and 0.7 μM, respectively). CID 2011756 also has antitumor activity.
体外研究：
CID 2011756 is an ATP-competitive PKD1 inhibitor, with an IC50 of 3.2 μM. CID 2011756 decreases the phosphorylation of endogenous PKD1 Ser916 in LNCaP cancer cells with an EC50 of 10±0.7 μM. CID 2011756 also has cellular pan-PKD inhibitory effects, with IC50s of 0.6±0.1 μM and 0.7±0.2 μM for PKD2 and PKD3, respectively.
CID 2011756 is an ATP competitive PKD inhibitor, with an IC50 of 3.2 μM for PKD1 in cell free assay, and also shows cellular pan-PKD inhibitory activity against PKD2 and PKD3 (IC50, 0.6 and 0.7 μM, respectively). CID 2011756 also has antitumor activity.
体外研究：
CID 2011756 is an ATP-competitive PKD1 inhibitor, with an IC50 of 3.2 μM. CID 2011756 decreases the phosphorylation of endogenous PKD1 Ser916 in LNCaP cancer cells with an EC50 of 10±0.7 μM. CID 2011756 also has cellular pan-PKD inhibitory effects, with IC50s of 0.6±0.1 μM and 0.7±0.2 μM for PKD2 and PKD3, respectively.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备