产品
编 号：F413788
分子式：C14H10Cl2NNaO2
分子量：318.13
分子式：C14H10Cl2NNaO2
分子量：318.13
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
50mg
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100mg
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200mg
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结构图
CAS No: 6385-02-0
产品详情
生物活性：
Meclofenamic acid (Meclofenamate) sodium is a non-steroidal anti-inflammatory agent (NSAID). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat - and obesity-related enzyme (FTO). Meclofenamic acid sodium has anti-inflammatory and antitumor activities.
体内研究：
Meclofenamic acid sodium (10 mg/kg/day, 腹腔注射, 连续 20 天) 在小鼠前列腺肿瘤模型中具有抗肿瘤活性。Animal Model:Prostate tumor model in mice
Dosage:10 mg/kg
Administration:i.p.
Result:Decreased tumor aggression, increased fibrosis, cellular proliferation and vascularity reduction.
体外研究：
Meclofenamic acid sodium (10, 100 200 mM, 4 天) 可抑制 haSMCs 的增殖和迁移。Meclofenamic acid sodium (4, 6 μM, 48 h) 联合吉非替尼诱导耐药 NSCLC 细胞 caspase 相关凋亡。
Meclofenamic acid (Meclofenamate) sodium is a non-steroidal anti-inflammatory agent (NSAID). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat - and obesity-related enzyme (FTO). Meclofenamic acid sodium has anti-inflammatory and antitumor activities.
体内研究：
Meclofenamic acid sodium (10 mg/kg/day, 腹腔注射, 连续 20 天) 在小鼠前列腺肿瘤模型中具有抗肿瘤活性。Animal Model:Prostate tumor model in mice
Dosage:10 mg/kg
Administration:i.p.
Result:Decreased tumor aggression, increased fibrosis, cellular proliferation and vascularity reduction.
体外研究：
Meclofenamic acid sodium (10, 100 200 mM, 4 天) 可抑制 haSMCs 的增殖和迁移。Meclofenamic acid sodium (4, 6 μM, 48 h) 联合吉非替尼诱导耐药 NSCLC 细胞 caspase 相关凋亡。
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