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编 号:F414672
分子式:C10H12FN5O3
分子量:269.23
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100mg
100
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2′-Deoxy-2′-fluoroadenosine can be used for the?synthesis?of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP.
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