产品
编 号:F417382
分子式:C6H10O4
分子量:146.14
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10mM*1mL in DMSO
询价
询价
500mg
160
In-stock
5g
400
In-stock
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生物活性:
Isosorbide (D-Isosorbide), an orally active vasodilating agent that can be used for the research of heart failure and angina (chest pain). Isosorbide is also an oral hyperosmotic diuretic.

体内研究:
Isosorbide (5 mg/kg; a single p.o.) significantly increases the urine volume of rats within 2 hours which lasts through the 8 hour experimental period.Isosorbide (5 mg/kg; a single p.o. 30 min prior to gallium injection) significantly reduces the urinary concentrations of both gallium and calcium in rats.Isosorbide (5 mg/kg; p.o. 30 min prior to gallium injection for 6 d) results in the formation of fewer renal precipitates and histopathologic changes than in the nondiuresed animals.
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