产品
编 号:F419077
分子式:C19H24O7
分子量:364.39
产品类型
结构图
CAS No: 66018-41-5
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产品详情
生物活性:
LL-Z1640-4 is a potent p38/JNK signaling inhibitor. LL-Z1640-4 significantly diminishes p38 and JNK activation in HCC cells transfected with MLK4 siRNA. LL-Z1640-4 markedly attenuates ROS production induced by MLK4 knockdown. LL-Z1640-4 significantly reduces the apoptotic cells in HCC cells transfected with siMLK4.
体外研究:
LL-Z1640-4 markedly restores the number of cells in migration and invasion decreased by siMLK4, and significantly up-regulates expression of MMP2 and Vimentin.