产品
编 号：F420869
分子式：C28H37ClO7
分子量：521.04
分子式：C28H37ClO7
分子量：521.04
产品类型
规格
价格
是否有货
2500μg
询价
询价
结构图
CAS No: 66734-13-2
产品详情
生物活性：
Alclometasone dipropionate (Sch 22219) is a steroid compound. Alclometasone dipropionate can be used for the research of dermatitis and skin itch.
体内研究：
Alclometasone dipropionate (0.1% (20 μL); both sides of the ears; once) shows effects on tuberculin- and egg albumin-induced allergic reaction.Animal Model:Lewis rats with tuberculin-induced delayed allergic reaction
Dosage:0.1% (20 μL)
Administration:Both sides of the ears; 0.1% (20 μL) 3 h before and 2 h after tuberculin challenge
Result:Partially inhibited the increase in amount of dye leaked.
Animal Model:Brown-Norway rats with egg albumin-induced passive cutaneous anaphylaxis reaction
Dosage:0.1% (20 μL)
Administration:Both sides of the ears; 0.1% (20 μL) 6 h before egg albumin challenge
Result:Significantly suppressed the increase in amount of dye leaked in this passive cutaneous anaphylaxis reaction.
体外研究：
Alclometasone dipropionate (0.01-100 ng/mL; 24 h) suppresses cytokine production of CD3/CD2 stimulation with IC50s of 5.54, 1.76, 2.09, 0.89, 3.26 and 0.76 ng/mL for IL-2, IL-3, IL-4, IL-5, IFN-γ and GM-CSF, respectively in human PBMC.
Alclometasone dipropionate (Sch 22219) is a steroid compound. Alclometasone dipropionate can be used for the research of dermatitis and skin itch.
体内研究：
Alclometasone dipropionate (0.1% (20 μL); both sides of the ears; once) shows effects on tuberculin- and egg albumin-induced allergic reaction.Animal Model:Lewis rats with tuberculin-induced delayed allergic reaction
Dosage:0.1% (20 μL)
Administration:Both sides of the ears; 0.1% (20 μL) 3 h before and 2 h after tuberculin challenge
Result:Partially inhibited the increase in amount of dye leaked.
Animal Model:Brown-Norway rats with egg albumin-induced passive cutaneous anaphylaxis reaction
Dosage:0.1% (20 μL)
Administration:Both sides of the ears; 0.1% (20 μL) 6 h before egg albumin challenge
Result:Significantly suppressed the increase in amount of dye leaked in this passive cutaneous anaphylaxis reaction.
体外研究：
Alclometasone dipropionate (0.01-100 ng/mL; 24 h) suppresses cytokine production of CD3/CD2 stimulation with IC50s of 5.54, 1.76, 2.09, 0.89, 3.26 and 0.76 ng/mL for IL-2, IL-3, IL-4, IL-5, IFN-γ and GM-CSF, respectively in human PBMC.
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