产品
编 号:F424402
分子式:C28H46O
分子量:398.66
产品类型
结构图
CAS No: 67-96-9
联系客服
产品详情
生物活性:
Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) .
体内研究:
Dihydrotachysterol is a potent synthetic vitamin D analogue that is widely available but more expensive than vitamin D2. It has an onset of action and half-life between those of vitamin D2 and calcitriol. Dihydrotachysterol (initially given at 0.03 to 0.08 mg/kg/day for 2 to 3 days. The final dosages range from 0.004 to 0.04 mg/kg/day) is useful for the treatment of hypoparathyroidism.Animal Model:Animal Model: Five young to middle-aged cats of mixed breeding
Dosage:Initially given at a dosage ranging from 0.03 to 0.08 mg/kg/day for 2 to 3 days. The final dosage ranged from 0.004 to 0.04 mg/kg/day.
Administration:Oral administration
Result:Was useful for the treatment of hypoparathyroidism.
体外研究:
Dihydrotachysterol is effective in the elevation of serum calcium by stimulating intestinal calcium absorption and mobilizing bone calcium in the absence of parathyroid hormone and of functioning renal tissue.Dihydrotachysterol also increases renal phosphate excretion.