产品
编 号:F435911
分子式:C23H23N5O4
分子量:433.46
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
联系客服
产品详情
生物活性:
Meleagrin is a roquefortine C-derived alkaloid produced by fungi of the genus Penicillium and has antimicrobial and anti-proliferative activities. Meleagrin is a class of FabI inhibitor. Meleagrin is a lead c-Met inhibitory entity useful for the control of c-Met-dependent metastatic and invasive breast malignancies.

体内研究:
Meleagrin potently suppresses the invasive triple negative breast tumor cell growth in an orthotopic athymic nude mice model.

体外研究:
Meleagrin inhibits the growth of the human breast cancer cell lines MDA-MB-231, MDA-468, BT-474, SK BR-3, MCF7 and MCF7-dox.Meleagrin causes a dose-dependent inhibition of HGF-induced cell migration, and invasion of breast cancer cell lines.
产品资料