产品
编 号：F437156
分子式：C41H55N7O9
分子量：789.92
分子式：C41H55N7O9
分子量：789.92
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 72122-62-4
产品详情
生物活性：
β-Casomorphin, bovine (β-Casomorphin-7 (bovine) ) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.
体内研究：
β-Casomorphin, bovine (7.5×10?6 mol/day/kg ; i.g.; for 30 days) increases plasma insulin and decreased plasma glucagon of diabetic rats.β-Casomorphin, bovine (7.5×10?6 mol/day/kg ; i.g.; for 30 days) alters the changes of SOD, GPx, T-AOC, MDA and H2O2 in the kidney of diabetic rats.β-Casomorphin, bovine (7.5×10?6 mol/day/kg ; i.g.; for 30 days) reduces MDA (significantly) and H2O2 (non-significantly) level in the kidney compared to the diabetic rats.β-Casomorphin, bovine (7.5×10?6 mol/day/kg ; i.g.; for 30 days) alleviates high glucose-induced decreasement in SOD and GPx activity, increasement in MDA contents in the NRK-52E cells.Animal Model:Male Sprague-Dawley (SD) rats (200 g±10 g)
Dosage:7.5×10?6 mol/day/kg
Administration:Oral gavage; for 30 days
Result:Increased plasma insulin and decreased plasma glucagon of diabetic rats.
体外研究：
β-Casomorphin, bovine (0.1 μM; 30 minutes-24 hours) stimulates the secretion of mucin in DHE Cells after 8 h of treatment.β-Casomorphin, bovine (0.1 μM; 24 hours) induces an increase in rMuc2 and rMuc3 mRNA levels.β-Casomorphin, bovine do not modify the expression of rMuc1, rMuc4, and rMuc5AC.β-Casomorphin, bovine (0.1 μM; 24 hours) stimulates MUC5AC expression and mucin Secretion in HT29-MTX Cells (human).
β-Casomorphin, bovine (β-Casomorphin-7 (bovine) ) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.
体内研究：
β-Casomorphin, bovine (7.5×10?6 mol/day/kg ; i.g.; for 30 days) increases plasma insulin and decreased plasma glucagon of diabetic rats.β-Casomorphin, bovine (7.5×10?6 mol/day/kg ; i.g.; for 30 days) alters the changes of SOD, GPx, T-AOC, MDA and H2O2 in the kidney of diabetic rats.β-Casomorphin, bovine (7.5×10?6 mol/day/kg ; i.g.; for 30 days) reduces MDA (significantly) and H2O2 (non-significantly) level in the kidney compared to the diabetic rats.β-Casomorphin, bovine (7.5×10?6 mol/day/kg ; i.g.; for 30 days) alleviates high glucose-induced decreasement in SOD and GPx activity, increasement in MDA contents in the NRK-52E cells.Animal Model:Male Sprague-Dawley (SD) rats (200 g±10 g)
Dosage:7.5×10?6 mol/day/kg
Administration:Oral gavage; for 30 days
Result:Increased plasma insulin and decreased plasma glucagon of diabetic rats.
体外研究：
β-Casomorphin, bovine (0.1 μM; 30 minutes-24 hours) stimulates the secretion of mucin in DHE Cells after 8 h of treatment.β-Casomorphin, bovine (0.1 μM; 24 hours) induces an increase in rMuc2 and rMuc3 mRNA levels.β-Casomorphin, bovine do not modify the expression of rMuc1, rMuc4, and rMuc5AC.β-Casomorphin, bovine (0.1 μM; 24 hours) stimulates MUC5AC expression and mucin Secretion in HT29-MTX Cells (human).
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