产品
编 号:F439465
分子式:C15H12FNOS
分子量:273.33
产品类型
结构图
CAS No: 727664-91-7
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产品详情
生物活性:
MLS0315771 is a potent and biologically active competitive phosphomannose isomerase (MPI) inhibitor, with an IC50 ~1 μM and a Ki of 1.4 μM.
体外研究:
MLS0315771 increases mannose flux toward glycosylation.MLS0315771 toxicity at higher concentrations is an off-target effect. MLS0315771 is toxic to the zebrafish embryos above 2 μM. At 8-10 μM, ~50% embryos appeare sick within 20 min, and most of them die by 30-60 min.