产品
编 号：F443960
分子式：C12H11NO5
分子量：249.22
分子式：C12H11NO5
分子量：249.22
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
5mg
询价
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10mg
询价
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25mg
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结构图
CAS No: 73912-52-4
产品详情
生物活性：
MS15203 is a potent and selective GPR171 agonist. MS15203 increases food intake and body weight. MS15203 increases neuronal activity. MS15203 significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP.
体内研究：
MS15203 (MS0015203) (3 mg/kg; i.p.) causes an increase in neuronal activity within cells containing GPR171 in the PVN..MS15203 (3 mg/kg; i.p.) significantly increases food intake at 4 and 8 hours.MS15203 (3 mg/kg; i.p.) significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP.
体外研究：
MS15203 (MS0015203) dose-dependently increases [S]GTPγS binding and inhibits adenylyl cyclase activity in rat hypothalamic membranes.
MS15203 is a potent and selective GPR171 agonist. MS15203 increases food intake and body weight. MS15203 increases neuronal activity. MS15203 significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP.
体内研究：
MS15203 (MS0015203) (3 mg/kg; i.p.) causes an increase in neuronal activity within cells containing GPR171 in the PVN..MS15203 (3 mg/kg; i.p.) significantly increases food intake at 4 and 8 hours.MS15203 (3 mg/kg; i.p.) significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP.
体外研究：
MS15203 (MS0015203) dose-dependently increases [S]GTPγS binding and inhibits adenylyl cyclase activity in rat hypothalamic membranes.
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