产品
编 号:F445280
分子式:C13H18ClN3O4S2
分子量:379.88
产品类型
结构图
CAS No: 742-20-1
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生物活性:
Cyclopenthiazide is a benzothiadiazine diuretic with antihypertensive properties. Cyclopenthiazide exerts a diuretic effect by inhibiting the reabsorption of sodium chloride and water at the distal renal tubules. Cyclopenthiazide increases the excretory capacity of the rat kidney.
体内研究:
Cyclopenthiazide (0.5 mg/kg; i.p.; daily, for 3 days; female Wistar rats) increases the excretion of p-aminohippurate (PAH) .Animal Model:Female Wistar rats
Dosage:0.5 mg/kg
Administration:Intraperitoneal injection; daily, for 3 days
Result:Stimulated p-aminohippurate (PAH) excretion.