产品
编 号:F458923
分子式:C22H32N6O12S2
分子量:636.65
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10mM*1mL in DMSO
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100mg
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500mg
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生物活性:
Ceftazidime (GR20263) pentahydrate , an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases.

体内研究:
Ceftazidime (2 h infusion of injection, 2 000 mg, every 8 h for 24 h) pentahydrate moderately reduces bacterial density in a murine thigh infection model.Animal Model:Murine thigh infection model
Dosage:2000 mg
Administration:2 h infusion of injection, every 8 h for 24 h.
Result:Reduced bacterial density against the isogenic NDM (New Delhi metallo-β-lactamase) strain.

体外研究:
Ceftazidime (0-8 μg/mL approximately, 24 h) pentahydrate displays antibacterial and anti-biofilm activities against P. aeruginosa strains.Ceftazidime (0-40 μg/mL approximately, 18-20 h) pentahydrate has inhibitory activities against S. maltophilia isolates.
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