产品
编 号:F465337
分子式:C176H302N52O41S
分子量:3834.67
产品类型
结构图
CAS No: 80451-05-4
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产品详情
生物活性:
Cecropin B has high level of antimicrobial activity and is considered as a valuable peptide antibiotic.
体内研究:
The wounds are moist with more exudation in C group, while that in other groups are dry without obvious exudation. The body temperature of the majority of the mice in each group is elevated, but the number of leucocytes in each group is lowered after operation. The quantity of bacteria in muscle in A group is obviously lower than that in M group and C group. The number of surviving mice after 4 PID in C group is evidently smaller than that in A and M groups( P<0. 05).
体外研究:
Cecropin B-induces NF-κB activation playing a pivotal role in the suppression of CYP3A29 through disrupting the association of the PXR/retinoid X receptor alpha (RXR-α) complex with DNA sequences. Cecropin B activates pig liver cells by interacting with TLRs 2 and 4, which modulated NF-κB-mediated signaling pathways.